If it's hurting you that much that you cant train or eat properly then yeah stop the Rad-140 ASAP. Nac is proven to lower liver toxicity with oral compounds such as rad Anavar etc. ( should have just Stopped there) but… thought I was being a pussy and got some oral liquid rad 140 from science bio and decided to hop on cycle. Started first 10 days with 10mg and now 20mg (first cycle of SARMS). Not worth dying for almost needed a transplant and never had any liver issues before. Side effect wise on me personally I tolerated the LGD better. Liver damage, kidney damage, hormone changes Get the Reddit app Scan this QR code to download the app now. I'm currently finishing up my 2nd week of my RAD-140 cycle (15mg ED). 5 2-4 weeks after ru + ketoconazole shampoo - on hand in case of hairloss dhea(25mg),nac,tudca,milkthistle Liver damage on RAD140 I have been on my first RAD140 cycle for 3 weeks (planned as 3 wks @ 5mg and 3 wks @ 10mg). A well managed cycle will not cause liver failure, but yes your enzymes will go up. I’m on my second week of rad-140 and my-677 from usgains and I Mar 29, 2023 · Background RAD140 (Testalone) is a novel selective androgen receptor modulator with very limited data currently available on adverse effects related to this compound. Most anabolics are injectable and have very little liver toxicity. Liver Support On RAD 140 + Cardarine ostarine is way more liver toxic than rad Your liver will be impacted…. Jan 3, 2020 · Alcohol consumption was insignificant. You will need TUDCA and NAC to support the liver. Both worked wonders for my liver and kidney enzymes. You can take NAC year round. 25mg a day from week 3 then 12. (Reference range was 5-45) ast was at the top of reference range at 40. toddtp. horny asf week 3 & 4. Avoid paracetamol and NSAIDs and asprin where possible. SARMs aren’t methylated don’t they don’t tax your liver like pro hormones or oral steroids do. You also should really look into RAD being liver toxic. Whereas I still enjoy good beers several days per week. I personally wouldn't ever buy from such an unprofessional site, these guys sound like idiots, I wouldn't trust their quality control. 2. **cycle :**wanted to do 6 to 8 weeks of 5mg ED of rad 140for PCT wanted to run enclo for the last 3 weeks and 2 weeks after the cycle actual experience : - after few hours of my first 5mg rad 140 went to the gym and already felt great pump ( placebo ? Overall diet/ lifestyle is bigger determining factor of liver condition and it can regenerate anyway. Gonna do the blood work tmrw. to avoid the headaches it's all about being hydrated and water/electrolyte intake. Recently, about 3-4 days ago, I noticed some mild liver discomfort. 2-1) Been taking 1200mg of NAC a day from the start. I’m 5’8 and 165lbs. Though all patients presented with jaundice, there was variability in symptom onset from agent cessation. Don't get the slow release though it is harsh on your liver. Jul 13, 2022 · DISCUSSION. 9-12 Similar to the previously reported cases, jaundice was My buddy doesnt drink, ever. For two weeks post cycle, I run 12. No Broscience, No misinformation. Things like chronically elevated blood pressure, fucked cholesterol, liver and kidney damage will slowly kill you over years Reply reply Virtual-State-918 We would like to show you a description here but the site won’t allow us. I’m curious how the liver toxicity of RAD would compare to say drinking a bottle of vodka each weekend, since it’s the methyl that causes the damage?… We would like to show you a description here but the site won’t allow us. I DID research and read quite a lot for several weeks before starting my cycle. Finished cycle of Rad 140 10mg and mk677 while lgd didn't raise my liver enzymes as much as rad or osta did, it still raised them, so it definitely does affect liver toxicity (here is a case where a guy induced liver injury with 10mg of lgd daily). I’m pretty skeptical and wouldn’t be super concerned about my liver with SARMs. Just talking about vitamins, liver support etc. I've heard LGD is awesome with a test base, but have also heard rad is a bit more powerful, and has prostate protection. So tbh these liver values aren’t the worst I’ve seen from folks running RAD. And yes, even low dose of rad will drop your test. Brought them down to low normal within a week. My first sarm cycle, 71kg -> 74kg ( 5,9 height). Rad isn’t even close. I was on my last week of rad when I had bloods taken. . Cause for my concern was my LDL was up significantly with HDL down. My thoughts on this is to bypass the liver. Please let me know what else you think this could be. Definitely do Cardio; it needs to be considered as an important segment of your entire fitness plan. Feb 17, 2023 · All were published in and after 2020. yes it will. Check your liver values before so you know where you start, rad didn’t hardly change my liver values which I was surprised so I’d say having a few drinks once a week or so won’t hurt you, I was also taking tudca Gram a day and 2-3 grams of NAC a day. Additionally the half life of RAD-140 would last another week after ceasing usage. Take 250 am and 250pm. Hey guys 3 days before finishing my RAD-140 cycle i got some liver problem ,no appetite , some sight of jaundice , fatigue , dark urine it destroy me… Jan 27, 2022 · Testolone RAD-140 is one of several selective androgen receptor modulators, that are currently undergoing testing and research as a potential testosterone alternative. Not pointless. I would say 10 mg is a good dosage with good results. RAD140 may be associated Been taking Rad 140 at 10mg sublingual for about a week now, I hold it there for 20 to 30 mins before swallowing. There’s no coming out of that. I drank a lot of water throughout the day. I’m thinking of using rad140 (pills) this will be my first time using a “sarm” I’m just wondering what is the safest route as in daily mg dosages. I suggest that you take 10mg every 16 hours. 5 mg 2 days on 2 days off (to control bloating) enclo(pct) - 6. Reddit iOS Reddit Android Reddit Premium About Reddit your symptoms are likely liver damage. My total testosterone went down from 905 before cycle to 278 now (see attached images). . They are promising therapeutics for patients with testosterone deficiency who cannot tolerate anabolic steroids due to their side effect profile. Looking to start my first cycle - Rad-140 MK-677 stack. DISCUSSION. true. [Meta] Took some rad 140 20mgs a day , and did blood work after taking pct for 4 weeks ,I waited 3 weeks to get bloods my test came out to 338 , it’s been 3 months since then redid blood work, and I came out to 469 should I start trt or will my test levels go back to base line ? Listen man just finished being in the hospital for rad 140 liver injury it was scary af my enzymes went to 3000 for alt and ast. Feel fine with slight fatigue but stacking with fat burner so compensates any fatigue. It was my decision not to use liver support because not everyone uses it and I wanted to check the effect on my own body. Would like to hear some experienced input! 1st cycle - Was advise by my sup shop to start @ 30mg a day of Rad 140 capsules (SP research products) . 8 To our knowledge, ours is the sixth case of SARM-associated drug-induced liver injury and the third case associated with RAD-140 use (). -It took a while for the RAD-140 to kick into full gear to where I saw my lifts jump. While NAC is great, it’s a shorter acting antioxidant of sorts for the liver. You will hold a lot of water with LGD which kind of makes you look bigger. All cases had no history of liver disease. Regardless I still recommend you supplement with some liver protectors. It's gonna be going against the liver itself. Get the Reddit app Rad 140/cardarine experience For my entire cycle I run an over-the-counter organ defender (Rich Piana liver and organ defender) which make sure it has NAC and Milk Thistle. rad 140 8 weeks 10mg ed first 6 weeks, 15mg ed last 2 weeks. Or check it out in the app stores Rad 140 liver support . Definite visual body and weight improvements. 26 U/L and Globulin was at 2. The eGFR is very low for a 25 year old male. I’m wondering how much NAC and how much milk thistle to take daily for liver support. Actually, in the scientific literature, there exist at least two case studies of liver damage on 10 mg LGD-4033 daily. I’m not talking about test support like enclo I have that sorted (6. 25 enclo ED from week 2-8, +2 weeks with no rad. It's prolonged periods of time that does it. Although there is not much research data to support it, based on user feedback, healthy individuals do not cause liver damage due to the use of appropriate doses of SARMS. Even if you took oral Tren or superdrol for 5 days it would be insanely unlikely to cause liver damage/failure. I can feel 10mg. Yes sir the milk thistle comepetes for the androgen receptors along with RAD140 and testosterone. We would like to show you a description here but the site won’t allow us. I did a rad cycle in September last year and had liver burns, i was taking omega 3s but no other liver support. Glad ur ok but I’m willing to bet you would’ve been fine if u didn’t drink on cycle. Oral anabolics are the same as sarms. 5 weeks into rad 140 cycle everything was completely normal except alt was 86. rad-140 - 10-20 mg ed mk 677 - 12. Do you drink alcohol, because you are only 19 days into your cycle and you only took low dose, liver damage shouldn’t be a problem unless you drink. In this report, we present two recently observed cases with distinct biochemical and histological phenotypes. Dosage dependent but it does work and has been proven with bloodwork. I'm running my 20mg rad cycle now for 12 weeks I'm 2 weeks in I get bloods again in 2 weeks 10 votes, 35 comments. From what it looks like, it is not mild on the liver at all even with liver support, so I will probably recheck my levels in a few days and stop taking it next week if they are above range. Rad is going to elevate you blood pressure slightly. I DID my pre-cycle bloods (actually, I check my bloods every 6-12 months) and my liver enzymes have always been within normal range. Science based discussion on harm reduction, and how to make the most of Rad140. Save tudca for going nuts on tren. Apr 11, 2024 · From this study, we can conclude that in 99% of the population, RAD 140 will not cause liver damage, but still, to be completely safe, take blood work before and after your Testolone cycle! It will also provide you with insight into your Testosterone levels, which will help you determine whether you need PCT or not. Both 10mg a day for 8 weeks. So let him take what he want, I’m 19 and have ran two rad 140 cycles. Stupid trade off and illogical. I am on my end of week 3 RAD 140 right now. Take fish oil, beet root, and magnesium if your BP goes up. So anyway, good chat and “”Now fuck outa here Why are you taking a multivitamin with extra vitamins on top? You know your liver has to process the rad-140 adding a bunch of vitamins is gonna make ur liver go into hyperdrive therefore increasing liver toxicity. Rad-140 elevated liver enzymes - Reddit true Jesus christ dude lol. NAC helps increase glutathione transport, which helps get rid of toxic metabolites in the liver, thus helping your AST/ALT levels. By the time I swallow it I can can barely taste it suggesting most of it has been absorbed. 03 g/dl. Your liver is going to be working over time for you and you need to treat is as well as you can (no booze, plenty of good nutrients, a good liver supp etc) On day 23 I did mid-cycle bloods: My liver enzymes (ALT & AST) are somewhat high (42 & 62). also for the sleep take rad in the morning and not at night, could help a little, or First of all, it’s doubtful whether that cycle even taxes your liver. On 3mg a day (week 2) and enjoying great recovery and pumps. Sarms are poison the results are cool at first but please I advice you don’t do it. 10mg of rad a day. I’d say I ran it for about 6 weeks 15 mg sometimes 20. Ahh name checks out 😂. I have no doubt that if I increased my dosages to the usual "body-building" level of 5 mg/day, I would be in red numbers. 5 days of binging on vodka straight will cause liver stress but certainly very unlikely to cause actual irreversible damage. RAD 140 is considered to be more anabolic than Ostarine, with side efffects that are slightly more prevalent than Ostarine. 25mg ed starting between week 2-4 and 12. Monitor your BP. Some people claim to have elevated liver enzymes on RAD, and some don’t. And could someone also comment recommendations to avoid any negative side effects such as suppression, liver damage and other long term side effects. 1. Appropriate blood tests and liver imaging excluded other liver diseases and biliary obstruction. Treat it like a cycle, u can't cover every base optimally without sacrificing results. -Dehydration. First SARM Rad -140 Cycle: Hey yall so I just made my first RAD-140 SARM Cycle plan this is all based off knowledge that I have since I'm still a bit new to this please if there is anything that needs addressing on my plan Especially Dosages and PCT 5 days is nothing. These are my results from the second blood test after RAD which I finished back in June. The half life of RAD 140 is 16 - 20 hours. Dosage: 10mg RAD-140 + 5mg Enclomiphene daily Sources: Receptor Chem and Chemyo Supplements: 1200mg NAC daily Other: I don't consume alcohol, but I do use the Wrecked pre-workout. So hella sketchy drug, but awesome at the same time. RAD-140 accumulates in the body so OP would likely have enough in his system to carry him through another week at a lower dose. All cases involved males between the ages of 19 and 40 years. Reply reply Safe873 Bro is talking out of his ass. 2 mg a day. Don't know why you didn't just do Test instead. But its way more risky and could lead to organ failure. Just part of taking orals. Run 300-400mg of test and use the Rad if you want or give it away Nac 1200mg. Free test is not commonly measured here unless you have a condition. 5mg of Enclo daily and an over the counter PCT (Rich Piana 5%) You will see more mass from the LGD. From week 4 to 8, I run 6. ASAT 455. This can happen due to a condition known as hepatorenal syndrome. The RAD is more of a hardening sarm with very Get the Reddit app Scan this QR code to download the app now liver support during 8 week rad-140 cycle. My libido wasn’t really affected whatsoever. fasting/ lots of water,/ heart n liver supps/ test optimiser etc anavar is metabolized mainly in the pancreas so it will barely affect your liver. Me personally. Subreddit for discussion about Rad140. This case of RAD-140–associated cholestatic liver injury had an assessed Drug-Induced Liver Injury Network causality score of 1 (probable) and a severity score of 3 (severe injury). The first-in-human phase 1 trial was recently published and did report a significant proportion of elevated aspartate aminotransferase, alanine transaminase, and total bilirubin among the test subjects. Ostarine causes higher liver values than RAD. Not kidding. pumps have been great. View community ranking In the Top 10% of largest communities on Reddit. When I got my blood work back I was completely shocked to see how much rad was causing liver toxicity . Also niacin for lipids. My mid-cycle blood test shows elevated ALT and AST, both 10 times the upper limit. Just had blood work done 2. RAD will be toxic to your liver, hence the ALT 250, the pain is probably referred pain due to inflammation of liver/capsule surrounding due to the cholestatic hepatotoxicity (the orally active RAD is beginning a cascade which stops your liver cells from properly excreting bile and their substances and they are dying Side effects of vosilasarm in preliminary clinical studies in women with metastatic breast cancer have included vomiting (27%), dehydration (27%), constipation, decreased appetite and weight loss (27%), hypophosphatemia, decreased sex hormone-binding globulin (SHBG) levels (100%), increased prostate-specific antigen (PSA) levels (80%), and abnormal liver function tests, including elevated Var gets metabolized by the kidneys so there is minimal to no liver damage. 5mg after for 2 weeks). 4 (range was 0. 25mg of Enclo daily. Think of it like drinking alcohol. (!) Estrogen is through the roof -- 103 pg/ml, x4 in 8 weeks. Take a great host of vitamins like Rich Pianas liver and organ defender. Ive been naturally training for about 2 years and I reckon I put on 8kg of lean muscle. Noticed some dull pain in the lower left side of my belly. Get the Reddit app Scan this QR code to download the app now Liver damage on RAD140 Just started RAD 140 cycle @25mg and MK 677 @20mg daily. Around at least 3 weeks. Alcohol can also directly cause kidney damage as well. It'll be my first AAS cycle, but I want to know if I should try out RAD-140 with it, or run a third LGD cycle. Hmmm, I don’t know the feeling, but saw that your liver enzymes were dubled as you replyed to a comment. 9-12 Similar to the previously reported cases, jaundice was I am currently running 20 mg of rad 140 and 20 of mk 677 Ed. Everything you are experiencing is within the realm of normal with SARM use. So I’m on week 5 of rad 140, was doing 15mg everyday for 4 weeks then started 20mg on the 5th my pre bloods were fine liver was a little high but… So I’m trying to learn a bit about sarms especially rad 140. 6 day a week workout with 2- 3 days cardio. Sorry first time on reddit not sure how this works But after people's recommendations (w/ legit answers) whether taking liver & kidney support supplements while on cycle will interfere with RAD-140 and affect gains? In contrast, the chemically related Andarine did not influence my liver in any significant way. My liver values did recover from RAD a few months later, my LDL was still bad but a bit better. I’ve had bloodwork done while on each separately. No, sarms are not easier on your liver than anabolics. This is only one persons bloods, and these numbers are abnormal for rad140 cycles. What would people recommend me using for cycle/liver support / doses etc. 20yo 205BW at Granted, your liver can heal with the use of N-acetyl cysteine (NAC) either taken orally or given IV; Kidney damage can occur as a complication of advanced liver disease, particularly in cases of acute liver failure. I have read a lot online and can’t find anything conclusive on wether or not rad140 has any liver toxic sides. Day by day… Hello. T Damn can people just stfu about his age, it’s his body no one else’s. RAD 140 tanked my HDL and raised my liver enzymes for subpar gains. after about 30 min it started getting worse and I threw up (surprisingly I threw only water and not food) like 5 times in a row. The agents used included ligandrol (n=4), Ostarine (n=2), and RAD-140 (n=1). The doctor has not asked for a follow up but I am a little concerned as there are a couple of issues in there. Take 600am and 600pm. Just alt was high, should I continue cycle or stop here? So it's stupid to be taking more additional substances that will cause damage, your kidneys are working hard enough. Also supplement with tudca 500mg. dbol and others that are metabolized in the liver are terrible for your health. Also the RAD is fairly "dry" and the LGD is fairly "wet". I ran one two week cycle of rad 140 at 20 15 mg pills then started feeling weird (test suppression) so I threw them away. I did not use PCT and my test levels were just over half way recovered I ended up losing most of the mass I made in 4 weeks, to be expected as my body didn't get used to needing that muscle. 6. Just watch out for liver disease symptoms and you should be fine. Also does NAC definitely help, will there be any negative interaction between RAD and NAC, should NAC be taken on cycle, what dose? Appreciate any advice :) We would like to show you a description here but the site won’t allow us. I would reccomend doing a couple months on tudca instead of NAC. Discussion preparing to do an 8 week rad-140 cycle, pct Dbol is safer than Rad But I added Rad to a test cycle because some doctor mentioned in a research paper that Rad should go well with trt I think it did help, wasn't on it long enough because other reasons, but recovery seemed better (hard to say if it was the Rad, probably was), effect was pretty quick “Steroid induced liver injury” so u got hammered on cycle and it’s the rads fault? I took 15mg rad alongside 10mg lgd for 12 weeks and my liver enzymes weren’t even above the normal range. Didn’t take any liver support and didn’t do blood work ( which is really stupid). I’m curious how the liver toxicity of RAD would compare to say drinking a bottle of vodka each weekend, since it’s the methyl that causes the damage? Or something with gene expression idrk. Pumps & muscles rock hard from week 3 onwards. Please explain in comments thanks 🙏 SARMs aren’t really worth using, especially without a test base. I will be running a liver support if I take it either way, just curious on thoughts of people who have used. Guess who has higher liver values between the two of us. Why not run basic Test a year on a oral will fuck your liver ( people get fucked lipids after 8 weeks ) can cause gyno it can cause appendicitis it can have permanent damage and people aren’t even gonna be able to help you because nobody ever ran this for a year , its a bad idea and you should reconsider everything 1 month into 10 mg rad-140, 15 mg mk-677 and 1 night of binge drinking (yeah I know that was stupid) liver enzymes came back alarmingly high. And I have found out different things from different people, but in general they are similar. I took NAC after a rad cycle. Bilirubin was 0. ALAT 127. Don’t make a post again unless it’s truthful and backed with reliable sources I had a terrible experience back in the pro hormone days with almost ruining my liver, fortunately no permanent damage. Just finished 1st bottle 90 caps(30 Days). I'm currently on week three of my RAD-140 cycle and wanted to share my test results and regimen to get some feedback and what to do next. Also 75mg of pharma grade var is super strong. Much less sides, the RAD I found very severe side effect wise. From the liver function test my AST was 66. Total cholesterol was roughly the same but I also had immature glucacytes in my blood as well leaving me to believe there might be minor liver damage from rad 140. Whilst the vitamins are combatting the effects of the toxicity dealt to ur liver. Ive been seriously considering steroids but I dont want to deal with major consequences nor do I want to become extremely bulky, I want to get up to 75-80kg and just maintain that weight, Ive been doing a bunch of research on SARMS and steroids and Ive Based on my bloods from my last two 8week 10mg and 15mg rad 140 cycles I had no liver or kidney red flags nor did my test suppress anymore then 15-20% or my natural value also my e2 stayed at a healthy level for both cycles. The gains are not worth it considering in the grand scheme of things you’re trading depression, lack of motivation, panic attacks, and risk of heart and liver damage for a dry muscle look. Im 16 years old, 68kg, about 15% BFP lean at 170cm. Within 6 weeks I had the liver levels of an eleven year old. Brother you need to look at the steroid wiki along with other places neither of those pieces of advice are correct and your friends have no clue what they are talking about. Tudca however will thin the bile and remove some of that stress from the gallbladder and liver. I have no clue if this shit was bunk. Liver histology showed moderate cholestasis with ductopenia and minimal fibrosis and inflammation, consistent with drug‐induced liver injury. -Lots of diarrhea. Lipid panel will be off, BP will rise, joints will hurt (fish oil will help a bit), insomnia, suppressed hunger, liver enzymes up. I’m now wondering about worst case scenarios after a 8-10 week cycle of 10mg/day. Reply. Rad on the other hand is hepatotoxic so it’s the opposite. Even though the gains are great even after 3 weeks, as I look noticably better and am stronger, it is not worth it if I have to spend the rest of the cycle I got back to my home country while still on cycle, started to feel a bit more depressed and stressed, so I decided to get my blood work. Throat was closing up a lot. On Thursday I started having dryness in my mouth, and drank alot of water. I do health cycle to take load off body after sarms/ hard training. Definitely worth looking at some liver supplements too if you're planning on doing 2x 8 weeks cycles close together. All in all, I really did enjoy the benefits of Chemyo’s RAD-140. Get the Reddit app Scan this QR code to download the app now What are the possible side effects of RAD-140 . There's no way around that while on cycle. Because when I tried 20 mg I needed to end early due to abdominal pain. Jun 6, 2021 · To date, two cases of liver injury associated with ligandrol and one with RAD 140 have been reported in the literature[14,15]. Far better than before rad even. it seems like Sarms mess with electrolyte balances in the body so for the first week you really want to be drink a lot of water and electrolyte drinks until your body self regulates that imbalance. Bloods after the cycle: Test went to down to 340 ng/dl, glucose stayed the same, liver is apparently feeling even better than before the cycle, HDL went down a bit, LDL stayed the same, kidneys no damage at all, blood count is looking good. xu nu vu oy nr tl ac xe ku om